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mt1  (Alomone Labs)


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    Structured Review

    Alomone Labs mt1
    Mt1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+mt1+receptor/Anti-Melatonin+Receptor+1A+Antibody/pm41366729-81-8-13
    Average 93 stars, based on 9 article reviews
    mt1 - by Bioz Stars, 2026-10
    93/100 stars

    Images

    Related Articles

    Immunofluorescence:

    Article Title: Relaxing effect of ramelteon on the uterus of non-pregnant and pregnant rats: Importance of melatonin receptors and BK Ca .
    Article Snippet: Aims: Our objective was to measure the effect and mechanism of action of the melatonin agonist ramelteon in rat uteri from non-pregnant and pregnant rats in vitro.. Main methods: KCl-induced contractions of non-pregnant and pregnant uterine rings samples (whole or endometrium-denuded) were investigated in an organ bath in the presence of ramelteon alone or with melatonin (MT) receptor antagonist luzindole or with the high-conductance calcium-dependent potassium channel (BKCa) blocker paxilline.. The changes in melatonin receptor expressions were followed by RT-PCR, Western blot, and fluorescent immunohistochemistry.

    Article Title: Ramelteon attenuates hippocampal neuronal loss and memory impairment following kainate-induced seizures.
    Article Snippet: Funding information National Research Foundation of Korea; Korea Basic Science Institute Abstract Evidence suggests that the neuroprotective effects of melatonin involve both receptor‐dependent and ‐independent actions.. However, little is known about the effects of melatonin receptor activation on the kainate (KA) neurotoxicity.. This study examined the effects of repeated post‐KA treatment with ramelteon, a selective agonist of melatonin receptors, on neuronal loss, cognitive impairment, and depression‐like behaviors following KA‐induced seizures.

    Incubation:

    Article Title: Relaxing effect of ramelteon on the uterus of non-pregnant and pregnant rats: Importance of melatonin receptors and BK Ca .
    Article Snippet: Aims: Our objective was to measure the effect and mechanism of action of the melatonin agonist ramelteon in rat uteri from non-pregnant and pregnant rats in vitro.. Main methods: KCl-induced contractions of non-pregnant and pregnant uterine rings samples (whole or endometrium-denuded) were investigated in an organ bath in the presence of ramelteon alone or with melatonin (MT) receptor antagonist luzindole or with the high-conductance calcium-dependent potassium channel (BKCa) blocker paxilline.. The changes in melatonin receptor expressions were followed by RT-PCR, Western blot, and fluorescent immunohistochemistry.

    Article Title: Ramelteon attenuates hippocampal neuronal loss and memory impairment following kainate-induced seizures.
    Article Snippet: Funding information National Research Foundation of Korea; Korea Basic Science Institute Abstract Evidence suggests that the neuroprotective effects of melatonin involve both receptor‐dependent and ‐independent actions.. However, little is known about the effects of melatonin receptor activation on the kainate (KA) neurotoxicity.. This study examined the effects of repeated post‐KA treatment with ramelteon, a selective agonist of melatonin receptors, on neuronal loss, cognitive impairment, and depression‐like behaviors following KA‐induced seizures.



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    Image Search Results


    Expression of MT1 and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Expression of MT1 and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

    Article Snippet: MT1 (AMR-031) , 1:200 , Rabbit , Alomone Labs, Jerusalem, Israel , AB_11218959.

    Techniques: Expressing, Comparison

    MT1 and MT2 immunoreactivity in TG. ( A ) positive MT1 immunoreactivity was observed in the cytoplasm and nuclei of TG neurons (thick arrows) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was observed predominantly in the cytoplasm of neurons (thick arrows), in some cases in their nuclei (thick arrows), and in Aδ-fibers (thin arrows). Negative cells are indicated by asterisks in both ( A ) and ( B ). Blue color represents nuclei staining with DAPI. ( C ) Bar graphs show the number of MT1 and MT2 immunoreactive TG neurons in male and female rats. There was no significant difference in MT1 or MT2 protein expression between sexes. However, the number of MT1-immunoreactive cells was approximately twofold higher than that of MT2 in both males and females. Data are presented as the mean ± SEM, n = 6 and * p < 0.05

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: MT1 and MT2 immunoreactivity in TG. ( A ) positive MT1 immunoreactivity was observed in the cytoplasm and nuclei of TG neurons (thick arrows) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was observed predominantly in the cytoplasm of neurons (thick arrows), in some cases in their nuclei (thick arrows), and in Aδ-fibers (thin arrows). Negative cells are indicated by asterisks in both ( A ) and ( B ). Blue color represents nuclei staining with DAPI. ( C ) Bar graphs show the number of MT1 and MT2 immunoreactive TG neurons in male and female rats. There was no significant difference in MT1 or MT2 protein expression between sexes. However, the number of MT1-immunoreactive cells was approximately twofold higher than that of MT2 in both males and females. Data are presented as the mean ± SEM, n = 6 and * p < 0.05

    Article Snippet: MT1 (AMR-031) , 1:200 , Rabbit , Alomone Labs, Jerusalem, Israel , AB_11218959.

    Techniques: Staining, Expressing

    Double immunohistochemistry of MT1 with CGRP or RAMP1 in TG. ( A ) CGRP (red fluorescence) was expressed in the cytoplasm of TG neurons (thick arrow) and in C- fibers (arrowhead). ( B ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( C ) The merged image shows that MT1 was co-localized with CGRP in the cytoplasm of small to medium-sized neurons (yellow, thick arrow). ( D ) RAMP1 (red fluorescence) was expressed in the cytoplasm of medium to large- sized TG neurons (thick arrow) and in Aδ-fibers (arrowhead). ( E ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( F ) Their co-localization (yellow) is seen in the merged image. MT1 was co-localized with RAMP1 in the cytoplasm of medium to large -sized neurons (thick arrow). Blue represents nuclei staining with DAPI

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Double immunohistochemistry of MT1 with CGRP or RAMP1 in TG. ( A ) CGRP (red fluorescence) was expressed in the cytoplasm of TG neurons (thick arrow) and in C- fibers (arrowhead). ( B ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( C ) The merged image shows that MT1 was co-localized with CGRP in the cytoplasm of small to medium-sized neurons (yellow, thick arrow). ( D ) RAMP1 (red fluorescence) was expressed in the cytoplasm of medium to large- sized TG neurons (thick arrow) and in Aδ-fibers (arrowhead). ( E ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( F ) Their co-localization (yellow) is seen in the merged image. MT1 was co-localized with RAMP1 in the cytoplasm of medium to large -sized neurons (thick arrow). Blue represents nuclei staining with DAPI

    Article Snippet: MT1 (AMR-031) , 1:200 , Rabbit , Alomone Labs, Jerusalem, Israel , AB_11218959.

    Techniques: Immunohistochemistry, Fluorescence, Staining

    Localization of MT1 immunoreactivity in the SPG and its co-localization with VIP and PACAP. ( A , D and G ) MT1 immunoreactivity (green) was observed in both the cytoplasm and nuclei of SPG neurons (thick arrows), as well as in SGCs (arrowheads). ( B and E ) VIP immunoreactivity (red) was detected in the cytoplasm of SPG neurons (thick arrows) and in a few C-fibers (arrowhead). ( C and F ) MT1 was co-localized with VIP in the cytoplasm of some SPG neurons (yellow-orange, thick arrows). D , E and F are higher-magnification views of images A , B and C , respectively. ( H ) PACAP immunoreactivity (red) was found in both the cytoplasm and nuclei of some SPG neurons (thick arrow). ( I ) MT1 was co-localized with PACAP in SPG neurons as shown in merged images (yellow/orange, thick arrow)

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Localization of MT1 immunoreactivity in the SPG and its co-localization with VIP and PACAP. ( A , D and G ) MT1 immunoreactivity (green) was observed in both the cytoplasm and nuclei of SPG neurons (thick arrows), as well as in SGCs (arrowheads). ( B and E ) VIP immunoreactivity (red) was detected in the cytoplasm of SPG neurons (thick arrows) and in a few C-fibers (arrowhead). ( C and F ) MT1 was co-localized with VIP in the cytoplasm of some SPG neurons (yellow-orange, thick arrows). D , E and F are higher-magnification views of images A , B and C , respectively. ( H ) PACAP immunoreactivity (red) was found in both the cytoplasm and nuclei of some SPG neurons (thick arrow). ( I ) MT1 was co-localized with PACAP in SPG neurons as shown in merged images (yellow/orange, thick arrow)

    Article Snippet: MT1 (AMR-031) , 1:200 , Rabbit , Alomone Labs, Jerusalem, Israel , AB_11218959.

    Techniques:

    MT1 and MT2 immunoreactivity in the DRG. ( A ) MT1 expression in DRG was observed in both the cytoplasm and nuclei of neurons (thick arrow) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was localized in the cytoplasm of neurons and in some cases in their nuclei (thick arrow), and in the Aδ-fibers (thin arrows). The blue color represents nuclei staining with DAPI

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: MT1 and MT2 immunoreactivity in the DRG. ( A ) MT1 expression in DRG was observed in both the cytoplasm and nuclei of neurons (thick arrow) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was localized in the cytoplasm of neurons and in some cases in their nuclei (thick arrow), and in the Aδ-fibers (thin arrows). The blue color represents nuclei staining with DAPI

    Article Snippet: MT1 (AMR-031) , 1:200 , Rabbit , Alomone Labs, Jerusalem, Israel , AB_11218959.

    Techniques: Expressing, Staining

    Immunohistochemistry of MT1 expression in the wall of cerebral arteries. ( A and B ) MT1 immunoreactivity (red) was observed in all layers of the basilar artery (thick arrows), i.e., in the adventitia layer and the endothelium as well as in the smooth muscle cells. Green represents the internal elastic lamina, autofluorescence (arrowhead in B ) and blue represents nuclei staining with DAPI

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Immunohistochemistry of MT1 expression in the wall of cerebral arteries. ( A and B ) MT1 immunoreactivity (red) was observed in all layers of the basilar artery (thick arrows), i.e., in the adventitia layer and the endothelium as well as in the smooth muscle cells. Green represents the internal elastic lamina, autofluorescence (arrowhead in B ) and blue represents nuclei staining with DAPI

    Article Snippet: MT1 (AMR-031) , 1:200 , Rabbit , Alomone Labs, Jerusalem, Israel , AB_11218959.

    Techniques: Immunohistochemistry, Expressing, Staining

    Expression of MT1 and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Expression of MT1 and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

    Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

    Techniques: Expressing, Comparison

    MT1 and MT2 immunoreactivity in TG. ( A ) positive MT1 immunoreactivity was observed in the cytoplasm and nuclei of TG neurons (thick arrows) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was observed predominantly in the cytoplasm of neurons (thick arrows), in some cases in their nuclei (thick arrows), and in Aδ-fibers (thin arrows). Negative cells are indicated by asterisks in both ( A ) and ( B ). Blue color represents nuclei staining with DAPI. ( C ) Bar graphs show the number of MT1 and MT2 immunoreactive TG neurons in male and female rats. There was no significant difference in MT1 or MT2 protein expression between sexes. However, the number of MT1-immunoreactive cells was approximately twofold higher than that of MT2 in both males and females. Data are presented as the mean ± SEM, n = 6 and * p < 0.05

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: MT1 and MT2 immunoreactivity in TG. ( A ) positive MT1 immunoreactivity was observed in the cytoplasm and nuclei of TG neurons (thick arrows) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was observed predominantly in the cytoplasm of neurons (thick arrows), in some cases in their nuclei (thick arrows), and in Aδ-fibers (thin arrows). Negative cells are indicated by asterisks in both ( A ) and ( B ). Blue color represents nuclei staining with DAPI. ( C ) Bar graphs show the number of MT1 and MT2 immunoreactive TG neurons in male and female rats. There was no significant difference in MT1 or MT2 protein expression between sexes. However, the number of MT1-immunoreactive cells was approximately twofold higher than that of MT2 in both males and females. Data are presented as the mean ± SEM, n = 6 and * p < 0.05

    Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

    Techniques: Staining, Expressing

    Double immunohistochemistry of MT1 with CGRP or RAMP1 in TG. ( A ) CGRP (red fluorescence) was expressed in the cytoplasm of TG neurons (thick arrow) and in C- fibers (arrowhead). ( B ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( C ) The merged image shows that MT1 was co-localized with CGRP in the cytoplasm of small to medium-sized neurons (yellow, thick arrow). ( D ) RAMP1 (red fluorescence) was expressed in the cytoplasm of medium to large- sized TG neurons (thick arrow) and in Aδ-fibers (arrowhead). ( E ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( F ) Their co-localization (yellow) is seen in the merged image. MT1 was co-localized with RAMP1 in the cytoplasm of medium to large -sized neurons (thick arrow). Blue represents nuclei staining with DAPI

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Double immunohistochemistry of MT1 with CGRP or RAMP1 in TG. ( A ) CGRP (red fluorescence) was expressed in the cytoplasm of TG neurons (thick arrow) and in C- fibers (arrowhead). ( B ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( C ) The merged image shows that MT1 was co-localized with CGRP in the cytoplasm of small to medium-sized neurons (yellow, thick arrow). ( D ) RAMP1 (red fluorescence) was expressed in the cytoplasm of medium to large- sized TG neurons (thick arrow) and in Aδ-fibers (arrowhead). ( E ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( F ) Their co-localization (yellow) is seen in the merged image. MT1 was co-localized with RAMP1 in the cytoplasm of medium to large -sized neurons (thick arrow). Blue represents nuclei staining with DAPI

    Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

    Techniques: Immunohistochemistry, Fluorescence, Staining

    Localization of MT1 immunoreactivity in the SPG and its co-localization with VIP and PACAP. ( A , D and G ) MT1 immunoreactivity (green) was observed in both the cytoplasm and nuclei of SPG neurons (thick arrows), as well as in SGCs (arrowheads). ( B and E ) VIP immunoreactivity (red) was detected in the cytoplasm of SPG neurons (thick arrows) and in a few C-fibers (arrowhead). ( C and F ) MT1 was co-localized with VIP in the cytoplasm of some SPG neurons (yellow-orange, thick arrows). D , E and F are higher-magnification views of images A , B and C , respectively. ( H ) PACAP immunoreactivity (red) was found in both the cytoplasm and nuclei of some SPG neurons (thick arrow). ( I ) MT1 was co-localized with PACAP in SPG neurons as shown in merged images (yellow/orange, thick arrow)

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Localization of MT1 immunoreactivity in the SPG and its co-localization with VIP and PACAP. ( A , D and G ) MT1 immunoreactivity (green) was observed in both the cytoplasm and nuclei of SPG neurons (thick arrows), as well as in SGCs (arrowheads). ( B and E ) VIP immunoreactivity (red) was detected in the cytoplasm of SPG neurons (thick arrows) and in a few C-fibers (arrowhead). ( C and F ) MT1 was co-localized with VIP in the cytoplasm of some SPG neurons (yellow-orange, thick arrows). D , E and F are higher-magnification views of images A , B and C , respectively. ( H ) PACAP immunoreactivity (red) was found in both the cytoplasm and nuclei of some SPG neurons (thick arrow). ( I ) MT1 was co-localized with PACAP in SPG neurons as shown in merged images (yellow/orange, thick arrow)

    Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

    Techniques:

    MT1 and MT2 immunoreactivity in the DRG. ( A ) MT1 expression in DRG was observed in both the cytoplasm and nuclei of neurons (thick arrow) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was localized in the cytoplasm of neurons and in some cases in their nuclei (thick arrow), and in the Aδ-fibers (thin arrows). The blue color represents nuclei staining with DAPI

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: MT1 and MT2 immunoreactivity in the DRG. ( A ) MT1 expression in DRG was observed in both the cytoplasm and nuclei of neurons (thick arrow) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was localized in the cytoplasm of neurons and in some cases in their nuclei (thick arrow), and in the Aδ-fibers (thin arrows). The blue color represents nuclei staining with DAPI

    Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

    Techniques: Expressing, Staining

    Immunohistochemistry of MT1 expression in the wall of cerebral arteries. ( A and B ) MT1 immunoreactivity (red) was observed in all layers of the basilar artery (thick arrows), i.e., in the adventitia layer and the endothelium as well as in the smooth muscle cells. Green represents the internal elastic lamina, autofluorescence (arrowhead in B ) and blue represents nuclei staining with DAPI

    Journal: The Journal of Headache and Pain

    Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

    doi: 10.1186/s10194-025-02215-9

    Figure Lengend Snippet: Immunohistochemistry of MT1 expression in the wall of cerebral arteries. ( A and B ) MT1 immunoreactivity (red) was observed in all layers of the basilar artery (thick arrows), i.e., in the adventitia layer and the endothelium as well as in the smooth muscle cells. Green represents the internal elastic lamina, autofluorescence (arrowhead in B ) and blue represents nuclei staining with DAPI

    Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

    Techniques: Immunohistochemistry, Expressing, Staining